Sepax Monomix Dt20 Affinity Resin is a narrowly discrete polymethacrylate rigid base bead. It can be functionalized with a polyhydroxylated surface coating layer. This is accessible with a bio-inert surface and has a low non-specific binding. This is accessible with an efficient capture and release. Sepax Monomix Dt20 Affinity Resin is also used in the analysis and parting of ionizable pharmaceutical incipient. This resin is accessible for a standard mRNA purification condition. It is needed to maximize the general production efficiency. This is needed to reduce the process development time.
Sepax Monomix Dt20 Affinity Resin
Technical Specifications
Resin Type | Monomix dT(20) |
---|---|
Base Matrix | Hydrophilic polymethacrylate |
Particle Size D50 (µm) | 30 |
Average Pore Size (…) | 1000 |
Functional Group | Oligo dT20-mer |
Ligand Density | 2.1 mg dT20 / mL of resin |
mRNA Binding Capacity (mg/ml resin) | 2.0 mg |
Max Linear Flow Rate (cm/hr) | 1000 |
Operating Temperature („ƒ) | 4-65 |
pH Stability | 2-12 |
Operating Pressure | 100 bar (10 MPa) |
मोबाइल Phase Compatibility | Compatible with common salt buffers, organic/aqueous solutions (acetonitrile, ethanol, etc.), and common additives for mRNA purification |
Long-term Storage | Store in 20% ethanol aqueous solution, 2-25„ƒ. Do not freeze resin or column. |
CIP | 0.1-0.5M NaOH. Recommend to start with 0.1M NaOH to prolong resin life |
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